Rapid loading of intravenous lacosamide: Efficacy and practicability during presurgical video-EEG monitoring
نویسندگان
چکیده
منابع مشابه
O16: Long Term Video EEG (AC/DC) Monitoring
Long term video electro-encephalographic (EEG) monitoring (LTM) is defined as the continuous and synchronized recording of EEG and multimedia to analyze brain abnormalities. A conventional LTM system continuously records EEG in the frequency range of 0.5-70Hz. The data synchronization, the high-volume data management, the system reliability as well as noise reduction remain significant challeng...
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BACKGROUND The introduction of IV valproic acid (VPA) has facilitated its use in situations where oral administration is not feasible. The present study was designed to evaluate the safety of administration of undiluted VPA (20 or 30 mg/kg/min) administered intravenously at rates of 6 or 10 mg/kg/min. METHODS Forty patients received a VPA loading dose (20 or 30 mg/kg) at 6 or 10 mg/kg/min. He...
متن کاملSafety and tolerability of adjunctive lacosamide intravenous loading dose in lacosamide-naive patients with partial-onset seizures.
PURPOSE To examine the safety and tolerability of rapidly initiating adjunctive lacosamide via a single intravenous loading dose followed by twice-daily oral lacosamide in lacosamide-naive adults with partial-onset seizures. METHODS This open-label, multicenter trial, enrolled patients with epilepsy who were taking 1-2 antiepileptic drugs (AEDs) in one of four sequential cohorts containing 25...
متن کاملMultimodality peak lctal vital signs during video-EEG monitoring
PURPOSE To assess and compare peak, multimodal ictal vital signs (iVS) during epileptic seizures (ES) and psychogenic nonepileptic seizures (PNES). METHODS Between 4/1/2010 and 4/1/2011, 183 adults had video-EEG monitoring, with 96 consecutive patients meeting inclusion criteria. Heart rate (HR), oxygen saturation (SaO2), and blood pressure (BP) were obtained at baseline and during an ictus. ...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2012
ISSN: 0013-9580
DOI: 10.1111/j.1528-1167.2012.03651.x